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Open Access
Copyright: The authors. This article is an open access
article licensed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use,
distribution and reproduction in any medium, provided the work is properly
cited.
Review Article
(Published online : 06-02-2013)
11.
Role of candidate genes in regulation of embryonic survival and maternal
recognition of pregnancy in farm animals
- Rohit Kumar, P. W. Ramteke, Amar Nath and Satyendra P. Singh
Vet World. 2013; 6(5): 280-284
doi:
10.5455/vetworld.2013. 280-284
Abstract
Successful growth and development of the post-hatching blastocyst and pregnancy
establishment are results of the interaction between a competent embryo and a
receptive uterine environment. There are certain marker gene transcripts
identified which contribute and regulate the bidirectional channel of
communication during the pregnancy period in farm animals. The changes in
temporal gene expression in the endometrium are similar in pregnant and cyclic
animals up to the time of maternal recognition of pregnancy (MRP) when conceptus
derived factors affect expression of a large number of genes in pregnant
animals. In this review we have discussed a set of candidate genes expressed or
induced for MRP. There are certain genes playing important role in MRP in farm
animals, of which interferon-tau (IFNT), Ubiquitin Cross Reative Protein (UCRP),
Ghrelin, Aldoketoreductase-1B5 (AKR1B5), SERPINA14 are having esteemed role in
farm animals. These genes appear to have role in successful establishment of
pregnancy and expression of the cascade of signalling molecules. However, IFNT
was recognized as one of the earliest expressing gene specifically required for
maintenance of pregnancy.
Keywords: AKR1B5, ghrelin, interferan tau,
maternal recognition of pregnancy, SERPINA14
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